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Treatment response of wart lesions to sensitization by Candida antigen in comparison with cryotherapy

Evaluation of sensitization by Candida antigen in comparison with cryotherapy in treatment of wart lesions in patients referring to dermatology clinic of Quaem hospital

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015012016955N5
Enrollment
60
Registered
2015-11-26
Start date
2013-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

wart. common wart

Interventions

Intervention 1: Use of 1.1000 purified candida antigen solution (Greer, USA) intralesionally into greatest wart lesions every 3 weeks for 3 doses in intervention group. Intervention 2: Use of cryother
Treatment - Drugs
Use of 1.1000 purified candida antigen solution (Greer, USA) intralesionally into greatest wart lesions every 3 weeks for 3 doses in intervention group.
Use of cryotherapy with liquid nitrogen weekly for 10 weeks in control group.

Sponsors

Vice chancellor for research of Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients older than 15 years that have verucca vulgaris and plantar warts whom referred to dermatology clinic of Quaem hospital; no prior allergic response to mumps or Candida antisera; not be pregnant or lactating; no primary or iatrogenic immuno-supression; no infection with human immunodeficiency virus type 1( HIV1); no hypersensitivity to lidocaine; no previous treatment for wart during 1 month ago Exclusion criteria:Taking any treatment for wart during study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Lesion improvement rate. Timepoint: Weekly for cryotherapy until 10 weeks, every 3 weeks for Candida antigen until three doses. Method of measurement: Measuring the size of two largest perpendicular diameter of lesion in millimeter.

Secondary

MeasureTime frame
Side effects. Timepoint: Weekly for cryotherapy group and each 3 weeks for candida antigen group. Method of measurement: Clinical evaluation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Pouran Layegh

Mashhad University of Medical Sciences

layeghpo@mums.ac.ir+98 51 3801 2851

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026