Effect of gel Benzocaine 18% versus gel Menthol 10% and 5% on local dentistry injection pain in children 3 to 6 years old

Effect of gel Benzocaine 18% versus gel Menthol 10% and 5% on local dentistry injection pain in children 3 to 6 years old: a double-blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201501189014N53

Enrollment

180

Registered

2015-01-21

Start date

2012-12-30

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Injection pain. Pain, not elsewhere classified

Interventions

Intervention 1: putting gel Menthol 10% on the location of injection for 30 seconds. Intervention 2: putting gel Menthol 5% on the location of injection for 30 seconds. Intervention 3: putting gel

Treatment - Drugs

putting gel Menthol 10% on the location of injection for 30 seconds

putting gel Menthol 5% on the location of injection for 30 seconds

putting gel Benzocaine 18% on the location of injection for 30 seconds

Eligibility

Sex/Gender

All

Age

3 Years to 6 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) age of 3 to 6 years; (b) the first dentistry local anesthesia injection; (c) require to repair the first or second molar of the maxilla. Exclusion criteria: (a) restless child; (b) history of previous dentistry injection; (c) contraindication for anesthesia; (d) absence of the first or second molar of the maxilla; (e) havinf systemic, psychological, or mental disorder, (f) presence of oral abscess or lesions.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Measuring the pain severity. Timepoint: just after injection. Method of measurement: using VAS scale.	—

Secondary

Measure	Time frame
Nothing. Timepoint: Nothing. Method of measurement: Nothing.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Fatemeh Zeraati

School of Pharmacy

fatemez415@gmail.com+98 81 3838 1590

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026