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Esophageal cancer screening in Golestan province

Effects of a non-endoscopic screening program on esophageal cancer incidence and mortality in Golestan province of Iran- a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201501179124N2
Enrollment
12000
Registered
2015-02-15
Start date
2015-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Cancer. Malignant neoplasm of oesophagus

Interventions

Intervention 1: Intervention group: Capsule sponge examination for collecting cytological sampling form the esophagus. Intervention 2: Control group: No intervention.
Early detection
Intervention group: Capsule sponge examination for collecting cytological sampling form the esophagus
Control group: No intervention

Sponsors

Vice chancellor for research, Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Major criteria for inclusion: Age higher than 50 years; Living in Eastern Golestan for at least 10 years Major criteria for exclusion: History of malignant disease; liver cirrhosis; chronic renal failure

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Incidence of esophageal squamous cell carcinoma. Timepoint: After finishing the study. Method of measurement: Personal interview and reviewing patients' medical files.;Death from esophageal squamous cell carcinoma. Timepoint: After finishing the study. Method of measurement: Personal interview and reviewing patients' medical files.;Death from all causes. Timepoint: After finishing the study. Method of measurement: Personal interview and reviewing patients' medical files.

Secondary

MeasureTime frame
Incidence of esophageal adenocarcinoma. Timepoint: After finishing the study. Method of measurement: Personal interview and reviewing patients' medical files.;Change in quality of life. Timepoint: Before starting and after finishing the study. Method of measurement: Using a standard quality of life questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Gholamreza Roshandel

Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences

roshandel_md@yahoo.com; roshandel@goums.ac.ir00891732340835

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026