Evaluation of the effectiveness of preemptive analgesia in Combination of Pregabalin, Acetaminophen, Naproxin, Dextrometorhan in Radical neck dissection

Evaluation of the effectiveness of preemptive analgesia in combination of Pregabalin, Acetaminophen, Naproxin, Dextrometorhan in Radical neck dissection in Cancer institue of Imam khomeini Hospital

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015011620676N1

Enrollment

Registered

2016-03-19

Start date

2013-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain. Acute pain

Interventions

Intervention 1: to interventional group: pregabalin (2.5 mg/kg) dextrometorphan (0.3 mg/kg) Naproxin( 7mg/kg), acetaminophen (15mg/kg) orally 1 hour before surgery. Intervention 2: The control group w

Prevention

to interventional group: pregabalin (2.5 mg/kg) dextrometorphan (0.3 mg/kg) Naproxin( 7mg/kg), acetaminophen (15mg/kg) orally 1 hour before surgery.

The control group was not received the combination medicines

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients aged 18-60 years old; ASAps I; candidated for radical neck dissection surgery. Exclusion criteria:ASAps II and more; History of addiction; Drug history for: anti convulsant, anti depression; History of gastrointestinal problem; chronic neck pain before surgery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain score. Timepoint: At the interance to ward and after 2, 4, 6, 8, 12, 24 hours. Method of measurement: Universal Pain Assessment Tools (UPAT).	—

Secondary

Measure	Time frame
Total dose of morphine during 24 hours. Timepoint: At the end of 24 hours. Method of measurement: Patient's medical records.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Tavakoli

Tehran University of Medical Sciences

fahatv@yahoo.com+98 21 6119 2828

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026