Albumin Versus Hydroxyethyl Starch in Cardiopulmonary Bypass Surgery

Comparing the effects of 5% albumin and 6% hydroxyethyl starch 130/0.4 on glomerular filtration rate and serum creatinine when used as priming solutions for cardiopulmonary bypass pump.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015011620112N4

Enrollment

Registered

2015-02-04

Start date

2012-01-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerotic heart disease. Atherosclerotic heart disease

Interventions

Intervention 1: 500 milliliter human albumin 5% as a priming solution of cardiopulmonary bypass pump. Intervention 2: 500 milliliter 6% hydroxyethyl starch 130/0.4 as priming solution of cardiopulmona

Treatment - Drugs

500 milliliter human albumin 5% as a priming solution of cardiopulmonary bypass pump.

500 milliliter 6% hydroxyethyl starch 130/0.4 as priming solution of cardiopulmonary bypass pump

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients undergoing elective coronary artery bypass grafting; age between 30 - 60 . Exclusion criteria: chronic renal failure; cardiopulmonary by pass pomp time over 2 hours; Patients were underwent an emergency operation; infective endocarditis; preoperative coagulation disorder; liver insufficiency; a left ventricular ejection fraction of less than 50%; previous cardiac surgery; a hemoglobin level of less than 10 milligram per deciliter before surgery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Serum Creatinine. Timepoint: preoprative and every 24 houre to 72 hour postoperatively. Method of measurement: isotope dilution mass spectrometry.	—

Secondary

Measure	Time frame
Glomerular filtration rate. Timepoint: preoperative and Every 24 hour to 72 hour postoperatively. Method of measurement: isotope dilution mass spectrometry.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPooya Derakhshan

Birjand University of Medical Sciences

pooyaderkh@yahoo.com00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026