Comparison of sedation effects of sufentanil and midazolam with nitrous oxide in cataract surgery

Comparation of sedation sufentanil and midazolam with nitrous oxide in patients of cataract surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015011314333N28

Enrollment

100

Registered

2015-01-31

Start date

2014-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cataract surgery. Disorder of vitreous body, unspecified

Interventions

Intervention 1: The experiment group received a mixture of nitrous oxide (aspiration gas with oxygen made in Iran Darman Gaz) and oxygen company with ratio of %66 and %33 in Face mask with flow of 6 l

Treatment - Drugs

The experiment group received a mixture of nitrous oxide (aspiration gas with oxygen made in Iran Darman Gaz) and oxygen company with ratio of %66 and %33 in Face mask with flow of 6 lit/min while it

The experiment group received 5 Milligram of sufentanil (common treatment) (the injection of mic/ml made of Teharan Daroopakhsh company-Iran) and 1 milligram of IV midazolam 5 mg/ml (produced by Teh

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion: satisfaction of patients; candidates to cataract surgery; Exclusion: people under 18 or over 80; pregnant women; patients with chronic lung diseases; heart failure with chronic hypoxemia; addicts; patients who experienced general anesthesia or surgeries longer than 30 minutes.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Every 5 minutes before the surgery, beginning the surgery and during the surgery; after the surgery and before transferring the patient to recovery room. Method of measurement: Recording blood pressure with monitoring tools.;Heart beat. Timepoint: Every 5 minutes before the surgery, beginning the surgery and during the surgery; after the surgery and before transferring the patient to recovery room. Method of measurement: The number of heart beats recorded by monitoring tool.;Vain blood oxygen saturation. Timepoint: Every 5 minutes before the surgery, beginning the surgery and during the surgery; after the surgery and before transferring the patient to recovery room. Method of measurement: Based on ratio of vein blood oxygen saturation recorded by monitoring and pulse oximetry tools.;Patient movement. Timepoint: Beginning the surgery and every 5 minutes to the end of the surgery. Method of measurement: By the doctor.	—

Measure

Time frame

Blood pressure. Timepoint: Every 5 minutes before the surgery, beginning the surgery and during the surgery; after the surgery and before transferring the patient to recovery room. Method of measurement: Recording blood pressure with monitoring tools.;Heart beat. Timepoint: Every 5 minutes before the surgery, beginning the surgery and during the surgery; after the surgery and before transferring the patient to recovery room. Method of measurement: The number of heart beats recorded by monitoring tool.;Vain blood oxygen saturation. Timepoint: Every 5 minutes before the surgery, beginning the surgery and during the surgery; after the surgery and before transferring the patient to recovery room. Method of measurement: Based on ratio of vein blood oxygen saturation recorded by monitoring and pulse oximetry tools.;Patient movement. Timepoint: Beginning the surgery and every 5 minutes to the end of the surgery. Method of measurement: By the doctor.

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Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026