Vitiligo. Vitiligo
Conditions
Interventions
Intervention 1: Intervention group: NB-UVB phototherapy was administered on lesions of both sides of the body, three times per week on non consecutive days for 40 sessions or 4 months. Intervention 2
Treatment - Drugs
Intervention group: NB-UVB phototherapy was administered on lesions of both sides of the body, three times per week on non consecutive days for 40 sessions or 4 months.
Control group: Each patient acted as his/her own control as while NB-UVB phototherapy was administered on lesions of both sides of the body whereas Vitix® gel (ACM, France) was applied on just one sid
Sponsors
Vice Chancellor for Research of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
12 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Bilateral symmetrical lesions distributed on face or limbs that involving more than 10% of body surface; age>12 years; who had signed a written informed consent. exclusion criteria: pregnancy; breast feeding; any history of previous hypersensitivity to Vitix gel; having skin malignancy; history of immunosuppression or taking immunosuppressive drugs; any contraindications for phototherapy; previous treatment with phototherapy from 3 months ago; history of photosensitivity; history of psychologic disorders
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lesion improvement based on amount of repigmentation. Timepoint: Monthly for 4 months. Method of measurement: Calculation the repigmentation score according to a certain classification. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: Monthly. Method of measurement: Based on history, physical examination and observation of the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Pouran Layegh
Mashhad University of Medical Sciences
Outcome results
None listed