Withdrawal syndrome. ICD-10 F11.23 is a billable code used to specify a medical diagnosis of opioid dependence with withdrawal.
Conditions
Interventions
Intervention group: The patients are put on fentanyl with the initial dose of 50-100 microg/h. This dose will eventually be adjusted based on the patient response and alleviation of the signs and symp
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Addicted patients who are intubated and admitted to toxicology ICU are those with potential inclusion criteria. If their signs and symptoms of withdrawal initiate during ICU stay (with any severity of withdrawal) they will be included. Addiction will be confirmed by the history taken from the patients’ next of kin, positive urine tests, and initiation of clinical opiate withdrawal syndrome determined by clinical opiate withdrawal scale (COWS).
Exclusion criteria
Exclusion criteria: Patients with any other dependencies (such as dependency to benzodiazepines, SSRIs, etc) will be excluded. Patients who receive any medication for control of the addiction before initiation of the withdrawal signs and symptoms, will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to alleviation of withdrawal syndrome and the potency of treatment performed based on COWS scale. Timepoint: 0.5 and 2 hours post administration. Method of measurement: COWS Scale (Clinical Opiate Withdrawal Scale). | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to extubation- Development of complications. Timepoint: 1 and 2 weeks after ICU admission. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNasim Zamani
Shahid Beheshti University of Medical Sciences
Outcome results
None listed