Comparision of Dexmedetomidine and Midazolam effects in sedation for addicted patients

The investigation of Dexmedetomidine effect in sedation for addicted patients with Non-invasive ventilation

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015010720592N2

Enrollment

Registered

2016-03-19

Start date

2010-01-29

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sedation during Non Invasive Ventilation. Air-conditioner and humidifier lung

Interventions

Intervention 1: Intervention: Prescription Dexmedetomidine at start and 2, 8, 16, 24 hours after start of Non Invasive Ventilation. Intervention 2: Control group: Prescription of Midazolam at start a

Treatment - Drugs

Intervention: Prescription Dexmedetomidine at start and 2, 8, 16, 24 hours after start of Non Invasive Ventilation.

Control group: Prescription of Midazolam at start and 2, 8 ,16, 24 hours after start of Non Invasive Ventilation.

Eligibility

Sex/Gender

All

Age

25 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : ICU admitted; age between 25 to 75 years old; with clinical indication for NIV; Exclusion criteria: Positive urine test for drugs Concurrent underlying cardiac or pulmonary diseases; APACHE II scores>20;

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Sedation scale. Timepoint: Start of study,2,8,12,16,24 hours. Method of measurement: Richmond Agitation-Sedation Scale questionnare.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad Reza Hashemian

Masih Daneshvari Hospital

smrhashemian@sbmu.ac.ir iran.criticalcare@yahoo.com+98 21 2610 9512

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026