Covid-19. COVID-19 Disease
Conditions
Interventions
Use plasmapheresis three times with 60% replacement of albumin 5% for one week in patients admitted to the treatment plan after reviewing the study selection criteria, and if the patient's blood pre
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: age of patients ranged between 8 to 16 years2.COVID-19 POSITIVE3. interleukin above 6 4.Patients hospitalized in the intensive care unit5.Increased respiration rate (be30 beats / min), difficulty breathing, cyanosis of the lips6.Oxygen saturation percentage =93% .COVID-19 positive interleukin above 6 Patients hospitalized in the intensive care unit Increased respiration rate (be30 beats / min), difficulty breathing, cyanosis of the lips Oxygen saturation percentage =93%,PaO2 / FiO2 =300 mmHg Patients with covid-19 disease receiving antiretroviral therapy such as Favipiravir ,remdesivir, and kaletra have experienced an increase in interleukin and a cytokine storm during treatment.
Exclusion criteria
Exclusion criteria: Patients treated with other interleukin-lowering methods, such as Actemra
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygen percentage. Timepoint: One day before the procedure and one day and four days and seven days after the procedure. Method of measurement: Pulse Oximeter device.;Interleukin 6 level. Timepoint: Before the procedure and one day and six days and seven days after the three-phase plasmapheresis. Method of measurement: Lab kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Mohammad Reza Hashemian
Shahid Beheshti University of Medical Sciences
Outcome results
None listed