Cardiac Surgeries. Cardiac insufficiency Heart failure following cardiac surgery or due to presence of cardiac prosthesis
Conditions
Interventions
Intervention 1: Patients in the intervention group received a bolus aminophylline of 5 mg/kg before the surgery and a subsequent continuous infusion of 0.25 mg/kg/h for up to 48 h after the surgery.
Treatment - Drugs
Placebo
Patients in the intervention group received a bolus aminophylline of 5 mg/kg before the surgery and a subsequent continuous infusion of 0.25 mg/kg/h for up to 48 h after the surgery.
Control group: patients in the control group didn't take aminophylline.
Sponsors
Vice Chancellor for Research, Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: all patients undergoing cardiac surgery and can use Aminophylline. Exclusion criteria: patients with cardiac arrhythmia, tachycardia , patients with kidney damage in case of non oliguric, daily urine of patients who have obstructive uropathy, patients with congenital renal anomalies
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Diagnosis of Kidney Damage. Timepoint: Daily measurement: On the days before and after surgery and the second and third days after surgery. Method of measurement: Urine Output. | — |
Primary
| Measure | Time frame |
|---|---|
| Diagnosis of Kidney Damage. Timepoint: Daily measurement: On the days before and after surgery and the second and third days after surgery. Method of measurement: RIFLE scale: It based on the amount of creatinine and GFR calculated by the amount of kidney damage. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactPeyman Alishahi
Shiraz University of Medical Sciences
Outcome results
None listed