periodontitis. Periodontitis
Conditions
Interventions
Intervention 1: "Intervention group": Doxycycline(3 percent ) gel was manufactured by shahin khapour harmaceutical Laboratory,Tehran- Iran . Intervention 2: "Control group":Placebo gel of was prepared
Treatment - Drugs
"Intervention group": Doxycycline(3 percent ) gel was manufactured by shahin khapour harmaceutical Laboratory,Tehran- Iran .
"Control group":Placebo gel of was prepared in the same manner but without the active drug in it (Made by the shahin khakpour of Pharmaceutical Laboratory,Tehran- Iran .
Sponsors
Deputy of Research Council of Dental Branch Islamic Azad University of Tehran
Eligibility
Sex/Gender
All
Age
10 Years to No maximum
Inclusion criteria
Inclusion criteria: "Inclusion criteria": patients with diabetes mellitus type II (at least 3 months before diagnosis, and A fasting blood sugar level of more than 125 mg/dl) and has periodontal disease is a chronic moderate (has a clinical attachment level of 3-4 mm) peritonitis, minimum of 16 natural teeth, and no periodontal treatment in the prior 6 months, had an glycated a hemoglobin (HbA1c) value between 7- 9 percent at screening, had reported no changes in diabetes medications within the last 3 months, were in the care of a physician for their diabetes. "Exclusion criteria": pregnancy or lactation, history of allergy to drugs used in the study; smoking; diabetes related emergency within 30 days ago; use of nonsteroidal anti-inflammatory drugs; or taking low dose daily aspirin (75-325 mg); use of immunosuppressive medications; antibiotic use; dialysis; risk of bleeding complications; the type of disease periodontal (Aggressive); a history of periodontal treatment in the previous 6 months; orthodontic treatment; using the removal prostheses; extensive dental caries; dental abscesses or infections.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Periodontal pocket. Timepoint: 15 days. Method of measurement: Periodontal probe. | — |
Secondary
| Measure | Time frame |
|---|---|
| Glycated hemoglobin (HbA1c). Timepoint: 3 months. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmirhossein Farahmand
Dental Branch Islamic Azad University of Tehran
Outcome results
None listed