transplant cardiac surjery. Surgical operation with transplant of whole organ
Conditions
Interventions
Intervention 1: Prescribed 0.3ug / kg desmopressin with 2 ml volume before transplant surgery. Intervention 2: 2 mL of saline administered before transplantation.
Prevention
Prescribed 0.3ug / kg desmopressin with 2 ml volume before transplant surgery
2 mL of saline administered before transplantation
Sponsors
Vice Chancellor for Research and Technological Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: age between 20-70 years old; Heart transplant surgery exclusion criteria: History of previous surgery on chest; Bleeding disorders and hemophilia; Patients with preoperative coagulation tests and platelet be disrupted; Contraindications for use of DDAVP; History of deep vein thrombosis-hematologic disease- carotid plaque due to sever narrowing; Chronic obstructive pulmonary disease
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chest tube blood volume. Timepoint: During the first 24 hours after surgery. Method of measurement: cc with a calibrated container.;Blood volume required for transfusion. Timepoint: During the first 24 hours after surgery. Method of measurement: Based on the number of units transfused.;FFP volume required for transfusion. Timepoint: During the first 24 hours after surgery. Method of measurement: Based on the number of units injected. | — |
Secondary
| Measure | Time frame |
|---|---|
| Thrombin time. Timepoint: before and after transplant surjery. Method of measurement: According to the second with lab kit.;Platelet count. Timepoint: Before and after transplantat surjery. Method of measurement: Based on the number of platelets per ml of blood. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed