Evaluation of Lowsonia inermis (Henna) and Zataria multiflora (Shirazi thyme) in treatment of cutaneous leishmaniasis

Comparing the effect of Herbal paste mainly made of Lowsonia inermis, Zataria multiflora and opium, to Glucantime in the treatment of patients with cutaneous Leishmaniasis.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150105020570N3

Enrollment

120

Registered

2018-06-18

Start date

2018-05-10

Completion date

Unknown

Last updated

2018-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cutaneous leishmaniasis. Cutaneous leishmaniasis

Interventions

Intervention 1: Pour the ointment prepared from the mixture of henna and Shirazy thyme once a day for 14 days. Intervention 2: Control group: This group receives the glucantime drug used in the treat

Eligibility

Sex/Gender

All

Age

No minimum to 70 Years

Inclusion criteria

Inclusion criteria: confirmation of CL based on positive smear culture positive from lesion PCR positive Under 70 years old

Exclusion criteria

Exclusion criteria: pregnant women mother feeding their babies using immunodeficient drugs from three months ago using any treatment for leishmaniasis

Design outcomes

Primary

Measure	Time frame
Decreased inflammation, shrinkage of the wound, absence of parasite in the wound. Timepoint: 14 days,45days ,3 month. Method of measurement: Observation and measure of the lesion.	—

Secondary

Measure	Time frame
. Timepoint: . Method of measurement: .	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hossein Motazedian

Shiraz University of Medical Sciences

motazedm@sums.ac.ir+98 71 3230 5291

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026