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Povidone Iodine and wound infection

Comparison of wound irrigation with 1% Povidone Iodine solution and normal saline on wound infection rate of patients with simple traumatic wound; A randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201501038104N11
Enrollment
350
Registered
2015-01-25
Start date
2015-01-30
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound. Injury, poisoning and certain other consequences of external causes

Interventions

Intervention 1: Intervention: Irrigation of wound with 50 ml/cm of wound length with 1% Povidone Iodine solution. Intervention 2: Control Irrigation of wound with 50 ml/cm of wound lenght with normal
Treatment - Drugs
Intervention: Irrigation of wound with 50 ml/cm of wound length with 1% Povidone Iodine solution
Control Irrigation of wound with 50 ml/cm of wound lenght with normal saline solution

Sponsors

Iran University of Medical Sciences Vice Chancellor of Research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Simple Traumatic Wound; Age over 18 years old Exclusion Criteria: Human or Animal bite; Tendon, nerve or vessel involvement; More than 12 hours since trauma; Concomitant joint or bone injuries; Any other traumatic injury to other organs; Bullet or high energy shrapnel wounds; Those on Antibiotics, Immunosuppressive drugs or steroids before trauma; Cirrhosis, Chronic Renal failure, Diabetes; Acquired or congenital immune compromised patients; Prosthetic heart valve; Allergy to Iodine; Chronic substance or alcohol abuse

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Wound infection. Timepoint: 2, 5, 10 and 30 days after procedure. Method of measurement: Direct observation in days 2, 5 and 10 and telephone follow up 30 days after procedure.

Secondary

MeasureTime frame
Wound dehicense and skin irritation. Timepoint: 2, 5, 10 and 30 days after procedure. Method of measurement: Direct observation in days 2, 5, 10 after procedure and telephone follow up in day 30.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Zavareh

Iran University of Medical Sciences

mina_zavareh@yahoo.com+98 21 6652 5327

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026