Evaluation of the effect of Statin on patient with heart failure

Comparison of the effectiveness of statins vs placebo on vascular endothelial function in patients with diastolic heart failure and normal coronary angiography

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015010320538N1

Enrollment

Registered

2015-06-15

Start date

2014-11-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure. Left ventricular failure

Interventions

Intervention 1: In control group 8 weeks treatment with placebo. Intervention 2: In intervention group 8 weeks treatment with atorvastatin 20 mg daily.

Treatment - Drugs

In control group 8 weeks treatment with placebo

In intervention group 8 weeks treatment with atorvastatin 20 mg daily

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: age above 18y/o: diastolic heart failure;normal coronary angiography Exclusion criteria contraindication to statin therapy; indication for statin therapy according to 2013 AHA guideline for lipid management.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Flow mediated diameter of brachial artery. Timepoint: Before and after intervention (8 weeks). Method of measurement: Sonography test/Millimeters.	—

Secondary

Measure	Time frame
Lipid profile. Timepoint: Aftetr 8 week treatmnet. Method of measurement: Blood sample/ Mg/dl.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Kardooni

Ahvaz Jundishapur University of Medical Sciences ...

DRALIKA1982@GMAIL.COM00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026