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progestrone effect on pregnancy

Comparison of oral dydrogesterone with vaginal cyclogest for luteal support in IUI cycles

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015010220408N2
Enrollment
148
Registered
2015-01-18
Start date
2014-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Other complications associated with artificial fertilization. Noninflammatory disorders of female genital tract

Interventions

Intervention 1: Intervention: Duphaston(Oral Didrogesterone 10mg) 20mg , Twice daily until 12 weeks. Intervention 2: Intervention: Vaginal progesterone( Cyclogest 400 microgram) Daily until 12 weeks.
Treatment - Drugs
Intervention: Duphaston(Oral Didrogesterone 10mg) 20mg , Twice daily until 12 weeks.
Intervention: Vaginal progesterone( Cyclogest 400 microgram) Daily until 12 weeks

Sponsors

Vice chancellor for research, Shahid Beheshti University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria; Women younger than 35 years old with unexplained infertility; Proper ovulation; 2 open tubal; Not having severe or moderate problem of man and without a history of previous abdominal surgery. Exclusion criteria; Advanced endometriosis; Dense pelvic adhesion; Genital TB; Patients who did not reffer for following up.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy rate. Timepoint: two weeks after start of intervention. Method of measurement: Transvaginal ultrasonography and pregnancy test.

Secondary

MeasureTime frame
Miscariage rate. Timepoint: Until 24 weeks after start of intervention. Method of measurement: History, Physical exam, Ultrasonography.;Patients acceptance. Timepoint: Untill 12 weeks. Method of measurement: Questionare.;Progestrone serum level. Timepoint: one week after start of intervention. Method of measurement: measure of blood progestrone.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactrobabeh taheripanah

Infertility & Reproductive Health Research Centre - Shahid Beheshti of Medical Science

taheripanahf@gmail.com+98 21 2243 2558

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026