The back of hand wrinkles. Changes in skin texture
Conditions
Interventions
Intervention group: The participants in this study will receive a ready-to-inject syringe of Inship X Radiance (Calcium Hydroxyl Apatite + Lidocaine) produced by Nano Darou Pajuhan Pardis subcutaneou
Sponsors
Nano Darou Pajouhan Pardis Company
Eligibility
Sex/Gender
All
Age
30 Years to No maximum
Inclusion criteria
Inclusion criteria: Age over 30 years Moderate to very severe degree of hand wrinkles based on MHGS criteria Agree to use safe methods of contraception. Signing an informed consent form and agreed to follow up.
Exclusion criteria
Exclusion criteria: History of type 1 allergic reactions or anaphylaxis reaction Pregnant or lactating or planning to become pregnant in the near future while studying Allergy or sensitivity to lidocaine Use of antiplatelet drugs during 72 hours before treatment and anticoagulant drugs during 2 weeks before or during treatment. Any abnormality or history of surgery on the back of hand
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of subjects with improvement in back of hand wrinkles. Timepoint: 30 days after intervention. Method of measurement: Merz Hand Grading Scale (MHGS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Thickness and density of dermis. Timepoint: Before intervention and 6 months later. Method of measurement: Skin ultrasound.;Changes in the intensity of hand wrinkles. Timepoint: Before intervention and 6 months later. Method of measurement: Based on the GAIS (Global Aesthetic Improvement Scale). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAniseh Samadi
Tehran University of Medical Sciences
Outcome results
None listed