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Evaluation the effect of jujube fruit on skin hyperpigmentation

Evaluation the effect of Jujube fruit (Ziziphus jujuba L) on skin hyperpigmentation comparison to placebo control; a double blind randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150101020514N10
Enrollment
46
Registered
2021-01-14
Start date
2020-09-28
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperpigmentation. Other melanin hyperpigmentation

Interventions

Intervention 1: 1: Intervention group: jujube syrup, 1 tablespoon (7.5 cc), twice a day, 8 weeks. Intervention 2: Control group: 1 tablespoon (7.5 cc), twice a day, 8 weeks.

Sponsors

Jarf Anishan Navid Salamat company
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Skin Type (III -IV) Aged between 18 to 60 years Signed informed consent voluntarily and knowingly

Exclusion criteria

Exclusion criteria: Use any light sensitive drug within 3 months prior to the study Active skin disease at test area: rosacea, atrophy, acne, eczema Use of topical lightening products like AHA ,BHA and retinoid components within 21 days prior to the study Documented allergies to components of test product Use of contraceptive or any hormonal drugs History of laser treatment or dermabrasion or deep facial peels within the past 3 months difficulty swallowing (a condition that could impact digestion and/or absorption) Active smoker ( last 1 years) Current pregnancy/ breast feeding Systemic disease (diabetics, hepatic disease, uncontrolled hypothyroidism)

Design outcomes

Primary

MeasureTime frame
The numbers of skin spots, its size and percentage. Timepoint: At the beginning and after 8 weeks. Method of measurement: Visioface device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEnsiye Aafi

Tehran University of Medical Sciences

ensiye_affi@yahoo.com+98 21 8889 6836

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026