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Progestron in treatment traumatic brain injury

Evaluation of neuroprotective effect of progestron in moderate to severe traumatic brain injury

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014123020487N1
Enrollment
96
Registered
2015-06-10
Start date
2014-11-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diffuse Brain Injury. Diffuse Brain Injury

Interventions

Intervention 1: Intervention group: patients in treatment group was given intravenous progestron 1 milligram per kilogam per 12 hours for 5 days. Intervention 2: Control group:Then patients in Contr
Treatment - Drugs
Placebo
Intervention group: patients in treatment group was given intravenous progestron 1 milligram per kilogam per 12 hours for 5 days.
Control group:Then patients in Control group will give intravenous injectionable serum every 12 hour for 5 day

Sponsors

Ahvaz Jundi Shapour University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patients who suffered from sever traumatic brain injury that reffered to emergency departemant; They have Glasscow coma scale 4 to 8; They were not undergo surgery for any reason; They were not suffered from cardiopulmonary arrest Exclusion criteria: The patient who that undergo surgery for any reason; females who are pregnant

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Average Glosscow coma scale. Timepoint: preaddmition, 6 th day, 3 month after addmition. Method of measurement: Glosscow coma scale.

Secondary

MeasureTime frame
Average Glosscow outcome scale. Timepoint: At discharge time, 3 month later. Method of measurement: Glasscow outcome scale.;Duration of admission in intensive care unit before and after treatment in control and treatment group. Timepoint: In admission period. Method of measurement: Number of admission days.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr mohamad ardeshiri

Ahvaz Jundi Shapour University of Medical Science

ardeshiri.m@ajums.,ac.ir+98 61 3374 3032

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026