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Effect of propolis in pain of Endometriosis

The effect of propolis supplementation in reducing pain in patients with Endometriosis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141230020486N5
Enrollment
40
Registered
2023-10-14
Start date
2023-10-23
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Endometriosis of pelvic peritoneum. Condition 2: Endometriosis of rectovaginal septum and vagina. Endometriosis of pelvic peritoneum Endometriosis of rectovaginal septum and vagina

Interventions

Intervention 1: Intervention group: standard treatment (progesterone drugs) along with propolis tablets 500 mg twice a day for 4 months. These tablets are made by the pharmaceutical laboratory of the

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: All patients with a definite diagnosis of endometriosis by imaging and have pain due to endometriosis Age between 20-45 years old Use of standard progesterone hormone treatments Not using NSAID medications Not refer for infertility treatment BMI between 18.5 to 27.5 Not taking food supplements Obtaining the patient's informed consent

Exclusion criteria

Exclusion criteria: Use of hormonal contraception and IUD during the last 3 months Pregnancy or breastfeeding in the last 3 months The presence of any physical and mental disease Drug sensitivity to propolis

Design outcomes

Primary

MeasureTime frame
Endometriosis pain. Timepoint: Before the intervention and 4months after the intervention. Method of measurement: Visual Analogue Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeili Hafizi

Mashhad University of Medical Sciences

hafizil@mums.ac.ir+98 51 3802 2608

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026