polycystic ovarian syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention group: Laparoscopic ovarian drilling is performed on patients with polycystic ovarian syndrome resistant to clomiphene. Then, 3 and 6 months after surgery (or until pregnancy), the levels
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: Infertile women with polycystic ovarian syndrome who have not been pregnant despite having no protection for one year and have been resistant to at least 6 courses treatment with clomiphene Age between 20 to 35 years Normal spermogram of patient's spouse Normal patient hysterosalpingography Patient's consent to participate in the study
Exclusion criteria
Exclusion criteria: Presence of problems in the spermogram Report of tube obstruction in hysterosalpingography Patient's unwillingness to enter the study or at any stage of treatment Failure to follow up the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of ovarian drilling on hormones level in women with polycystic ovarian syndrome resistant to clomiphene. Timepoint: 3 and 6 months after the ovarian drilling (or until pregnancy), the level of Anti-Mullerian hormone, androgens, antral follicles and ovulation rates are checked. Method of measurement: The level of androgens (testosterone, DHEAS, androstenedione, and 17 hydroxyprogesterone), Anti-Mullerian hormone, the number of antral follicles by laboratory tests.;Effect of ovarian drilling on ovulation rate in women with polycystic ovarian syndrome resistant to clomiphene. Timepoint: 3 and 6 months after the ovarian drilling (or until pregnancy), ovulation rates are checked. Method of measurement: Ovulation levels are monitored by serial vaginal sonography from the second day of the cycle to ovulation time. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLeili Hafizi
Mashhad University of Medical Sciences
Outcome results
None listed