Skin rejuvenation. Other specified disorders of skin and subcutaneous tissue
Conditions
Interventions
Intervention 1: Topical anesthetic gel is
applied to both sides of face and left for 30minutes.
The patient's eyes are covered with a shield during the entire procedure. Patients are randomly assigned
which is focused to a spot
size of approximately 120 micrometer in diameter ,the pulse duration of 10 milliseconds and pulse energy varies from 5 to 70mJ .Three treatment sessions with 1 month interva
which is focused to a spot
size of approximately 250 micrometer in diameter ,the pulse duration of 400microseconds and total fluence of 60J/cm2 .Three treatment sessions with 1 month interval for each
Treatment - Other
Topical anesthetic gel is
applied to both sides of face and left for 30minutes.
The patient's eyes are covered with a shield during the entire procedure. Patients are randomly assigned to receive tr
which is focused to a spot
size of approximately 120 micrometer in diameter ,the pulse duration of 10 milliseconds and pulse energy varies from 5 to 70mJ .Three treatment sessions with 1 month interv
which is focused to a spot
size of approximately 250 micrometer in diameter ,the pulse duration of 400microseconds and total fluence of 60J/cm2 .Three treatment sessions with 1 month interval for eac
Sponsors
Shahid Beheshti University of Medical Science-Skin Research Center
Eligibility
Sex/Gender
Female
Age
35 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:females between 35 and 60years of age ;patients with mild to moderate facial rhytides at rest Exclusion criteria :males;females younger than 35 yerars old;pregnancy and lactatation;cosmetic procedures affecting the treatment area (e.g.,botulinum toxin,dermabrasion, chemical peeling, laser surgery, or face-lift)within the last 6months;oral isotretinoin within the last 6months; history of keloid formation
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin elasticity. Timepoint: before treatment_before each session_3month after the last session. Method of measurement: resonance running time/reviscometer.;Rhytides improvement. Timepoint: before treatment_before each session_3month after the last session. Method of measurement: improvment percentage_comparing digital photoghraphes by dermatologist.;Patient satisfaction. Timepoint: 1month after session 1&2-three month after session3. Method of measurement: percentage- Patient satisfaction questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects(pain-burning and stinging-erythem-edema-bulla-bleeding-crust formation-hypopigmentation-hyperpigmentation-scar-atrophy). Timepoint: one week after each treatment session. Method of measurement: patient evaluation with questionnaire-dermatologist evaluation.;Side effects lasting. Timepoint: until one week after each treatment. Method of measurement: day. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElmira Asadi
Skin Research Center
Outcome results
None listed