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On the efficiency of oral acetaminophen on artery closure among premature infants hospitalized in ICU

On the efficiency of oral acetaminophen on artery closure among premature infants hospitalized in ICU

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014122714333N26
Enrollment
66
Registered
2015-01-27
Start date
2014-05-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patent Ductus Arteriosus. Patent ductus arteriosus

Interventions

Experiment group included infants who were not treated through taking oral ibuprophen twice a day and were checked to be treated through taking oral acetaminophen with dose of 15 mg/kg every 6 hours f
Treatment - Drugs

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Months to No maximum

Inclusion criteria

Inclusion criteria: Inclusion: infants with contraindication using ibuprophen (oliguria: output less than 1cc/kg/hr. plackets less than 50000. Hyperbilirubinemia with the need to jaundice. Necrotizing enterocolitis perforation of the gastrointestinal tract); infants who were not treated through taking oral ibuprophen twice a day; infants with PDA determined by echocardiography. Exclusion: Congenital heart disease with the need to PDA to keep blood flow constant; life threatening infection; Intraventricular hemorrhage at 3 and 4 grades.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Patent or closure of Ductus Arteriosus. Timepoint: By a doctor. Method of measurement: At the beginning of the intervention and three after that.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026