Effect of HCG on pregnancy

Evaluation the effects of intrauterine Human Chorionic Gonadotropin injection on intracytoplasmic sperm injection –Embryo transfer cycles success rates.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014122320408N1

Enrollment

308

Registered

2015-01-18

Start date

2014-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diseases of the genitourinary system. Noninflammatory disorders of female genital tract

Interventions

Intervention 1: Intervention: In case group 5000 IU/ml of urinary human chorionic gonadotrophin diluted with with 1 ml of media and immedietly after oocyte recovery, Injected in to the uterine cavity

Treatment - Drugs

Intervention: In case group 5000 IU/ml of urinary human chorionic gonadotrophin diluted with with 1 ml of media and immedietly after oocyte recovery, Injected in to the uterine cavity by IUI catheter

Control group: Continues treatment without any intervention.

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Women aged 20-40 years undergoing fresh intracytoplasmic sperm injection -embryo transfer cycles that have normal endometrial thickness (7-12 milimeters) on the day of embryo transfer and thay dont have any visible endometrial pathology, And they have less than three failed previous intracytoplasmic sperm injection cycles, BMI 30, And duration of infertility is more than 10 years and severe male infertility.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rate. Timepoint: Five weeks after start of intervention. Method of measurement: Transvaginal ultrasonography.;Implantation rate. Timepoint: End of the treatment. Method of measurement: Statistical analysis.	—

Secondary

Measure	Time frame
Chemical pregnancy rate. Timepoint: Two weeks after embryo transfer. Method of measurement: Labratory kit.;Miscariage rate. Timepoint: Until 24 weeks after start of intervention. Method of measurement: History, physical exam, ultrasonography.;Fertilization rate. Timepoint: After embryo development. Method of measurement: Labratory investigation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRobabeh Taheripanah

Infertility & Reproductive Health Research Center Shahid Beheshti University of Medical Science

taheripanahf@yahoo.com+98 21 5530 1452

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026