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A randomized clinical trial for evaluation of the efficacy of ProGsterol on patients with Poly Cystic Ovary Syndrome (PCOS)

A randomized, parallel, double blind, placebo-controlled clinical trial for evaluation of the efficacy of ProGsterol versus placebo on patients with Poly Cystic Ovary Syndrome (PCOS) candidate for ART

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141223020408N7
Enrollment
200
Registered
2025-11-01
Start date
2025-11-26
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovarian syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: ProGsterol 3 grams sachet includes 30 mg Deglusterol, VIRA RAHESH Pharmed Pharmaceutical Co, Once a day, 45-60 minutes before breakfast. Intervention 2: Control gro

Sponsors

VIRA RAHESH PHARMED Pharmaceutical Co
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women with Poly Cystic Ovary Syndrome confirmed based on the Rotterdam criteria candidate for IVF

Exclusion criteria

Exclusion criteria: Endometrioma Uterus Myoma Women that their husband needs TESE or PESA Type 1 or 2 Diabetes Mellitus Inflammatory disease or Autoimmune disease Acute cardiovascular disease Liver disease Kidney disease Cancer Central hypogonadism

Design outcomes

Primary

MeasureTime frame
Number of oocytes. Timepoint: Before the intervention and 1 month after intervention. Method of measurement: Counting by microscope.;Embryo quality. Timepoint: 3 months after intervention. Method of measurement: Microscope.;Rate of Pregnancy. Timepoint: 4 months after intervention. Method of measurement: Counting.

Secondary

MeasureTime frame
Waist Hip Ratio. Timepoint: Before the intervention and 4 months after intervention. Method of measurement: Size assessment.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRobabeh Taheripanah

Shahid Beheshti University of Medical Sciences

mhrhrc@yahoo.com+98 21 2271 6383

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026