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Prophylactic Effect of Magnesium Sulfate on Intraocular Pressure Rising during Laparoscopic Cholecystectomy

The Effect of Magnesium Sulfate on Reducing Intraocular Pressure during Laparoscopic Cholecystectomy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014122219470N6
Enrollment
40
Registered
2015-01-09
Start date
2014-02-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Increased Intraocular Pressure. Ocular Hypertension

Interventions

Intervention 1: Intervention Group:The Magnesium Sulfate was Solved in 100cc Normal Saline and Infused within 20 Minutes in the Treatment Group. Intervention 2: Control group:100 cc Normal Saline was
Treatment - Drugs
Placebo
Intervention Group:The Magnesium Sulfate was Solved in 100cc Normal Saline and Infused within 20 Minutes in the Treatment Group
Control group:100 cc Normal Saline was Infused to Patients in the Control Group Before the Operation

Sponsors

Vice Chancellor for Research, Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Adult patients, ASA I and II, weighting between 50 to 80 kg, Patients who had been Scheduled for Laparoscopic Cholecystectomy. Exclusion criteria: Arrhythmia in ECG, Cardiac Disease, Musculoskeletal Diseases like Myasthenia Grove,Renal Failure, Acute or Chronic Eye Disease, History of Using any Drugs that Affects Intraocular Pressure.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Effect of Magnesium Sulfate on the Intraocular Pressure. Timepoint: During Larangoscopy and Intubation. Method of measurement: Tonopen.

Secondary

MeasureTime frame
Effect of Magnesium Sulfate on the Intraocular Pressure. Timepoint: During CO2 Insufflation. Method of measurement: Tonopen.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbdolsamad Saleh

Shiraz University of Medical Sciences

saleha@sums.ac.ir+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026