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Comparison of lidocaine and dexamethasone on gargle for sore throat and cough caused by general anesthesia.

Comparison of lidocaine and dexamethasone on gargle on pre-operative sore throat and coughing after extubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014122020336N2
Enrollment
120
Registered
2015-03-04
Start date
2015-04-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore throat. Acute pharyngitis

Interventions

Intervention 1: In the second group of 10 cc of distilled water for 10 seconds, gargle with dexamethasone in the sitting position. Intervention 2: The first group of patients in a sitting position for
Prevention
In the third group, 10 mL of saline gargle for 10 seconds in a sitting position
In the second group of 10 cc of distilled water for 10 seconds, gargle with dexamethasone in the sitting position
The first group of patients in a sitting position for 10 seconds to 10 cc of 1% lidocaine gargle

Sponsors

Vice chancellor for research, Gonabad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ASA physical status I to II; aged 18 to 80 years; surgical procedures under general anesthesia with orotracheal intubation in the supine position; not using corticosteroids and analgesics before operation. exclusion criteria: patients undergoing oral cavity surgery; cervical spine surgery; thyroid surgery;patients with a difficult airway (after >2 orotracheal intubation attempt. requiring a nasogastric tube;or a history of perioperative sore throat. Patients with operation time less than 60 minute and more than 180 minutes

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sore throat. Timepoint: In the recovery room after full consciousness, 6 h, 12 h and 18 h after surgery. Method of measurement: Questionnaire.

Secondary

MeasureTime frame
Cough. Timepoint: In the recovery room after full consciousness, 6 h, 12 h and 18 h after surgery. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad Mirzaee

Gonabad University of Medical Sciences

mirzaee.a@gmu.ac.ir; sarcheshme89@gmail.com+98 51 5722 3028

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026