Comparison of effectiveness of the bioadhesive pastes curcumin and topical corticosteroid for the treatment of Aphthous Stomatitis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141220020377N5

Enrollment

Registered

2021-10-02

Start date

2021-09-09

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent oral aphthae. Recurrent oral aphthae

Interventions

Intervention 1: Control: Triamcinolone in oral base Ointment (Triadent), topical use in oral mucosa ulcer, 3 time/day, after meal, for 10 days. Intervention 2: Intervention: Curcumin Gel-topical use i

Eligibility

Sex/Gender

All

Age

12 Years to 79 Years

Inclusion criteria

Inclusion criteria: Patients with RAS symptoms for less than 1 day

Exclusion criteria

Exclusion criteria: The patients who did not sign the letter of informed consent Patient with hypertension (greater than 80/130) cases suspected of Behcet's syndrome, inflammatory bowel disease. Pregnant or lactating women Patients with Diabetes Patients Use of systemic aphthous treatment (over the past three months) and topical treatment during the procedure Atypical aphthous cases Patients with RAS symptoms for more than 1 day

Design outcomes

Primary

Measure	Time frame
Pain sensation. Timepoint: before starting study,days 1,4 ,7 ,10. Method of measurement: Use of visual analoge scale (VAS) from 0- 10, 0: no pain.	—

Secondary

Measure	Time frame
Recurrent aphthous ulcers. Timepoint: days 1,4,7,10. Method of measurement: Measuring of ulcers by ruler.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTahereh Nosratzehi

Zahedan University of Medical Sciences

Nosratzehim@yahoo.com+98 54 3411 3041

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026