Pregabalin in trauma pain control

Comparison of intravenous morphine with morphine plus Pregabalin in trauma patients with extremities' fracture and severe pain

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201412198104N10

Enrollment

150

Registered

2015-01-25

Start date

2015-01-30

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain in extrimity fracture. Injury, poisoning and certain other consequences of external causes

Interventions

Treatment - Drugs

Intervention group receive morphine 5mg and pregabalin 300mg

Control group will receive morphine 5 mg and placebo.

Intervention 1: Intervention group receive morphine 5mg and pregabalin 300mg. Intervention 2: Control group will receive morphine 5 mg and placebo.

Eligibility

Sex/Gender

All

Age

15 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Trauma patients with extremity fracture; Verbal Numeric pain score more than 6; Age between 15 or 60 Exclusion Criteria Addiction; Any contraindication for morphine or Pregabalin; Any other distracting injury; Inability to cooperate

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of pain. Timepoint: 0-10 minutes-30 minutes- 1 hour- 6 hours- 12 hours- 18 hours and 24 hours after intervention. Method of measurement: Using Verbal Numerical Rating Scale (VNRS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Amin Zare

Iran University of Medical Sciences

mazare74@yahoo.com+98 21 6652 5327

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026