Female Infertility. Female infertility
Conditions
Interventions
Intervention 1: Intervention group:In all patients, ovarian stimulation is initiated according to the antagonist protocol and immediately after the follicle reaches 17 mm at the same time as oocyte re
2 cc of enriched platelet solution (PRP) is injected into each ovary under anesthesia and then IVF steps are performed. Intervention 2: Control group: In this group, PRP is not performed and only rout
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: The second cycle of embryo transfer Criteria for detecting poor ovarian function based on the Bologna criterion Age less than 45 years History of having at least three oocytes in the previous cycle AMH hormone less than 1.1 ng / ml BMI less than 30kg/m2 At least ten million sperm and three percent sperm with a normal morphology
Exclusion criteria
Exclusion criteria: Immunological diseases Hematological diseases Chromosomal or genetic disorder Uterine disorders Hemoglobin level less than 11 grams per deciliter Platelets less than one hundred and fifty thousand per cubic millimeter Systemic use of corticosteroids within two weeks before the procedure Hypothyroidism Respiratory tract infections Kidney failure Endometriosis Sub mucusal myoma Asherman Syndrome Pathology of the Fallopian tubes (Hydrosalpinx) Endocrine diseases Endocrine diseases Allergic reactions The dissatisfaction of the patient to continue treatment No contraindications for pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of oocyte. Timepoint: Two months after the PRP. Method of measurement: Vaginal Sonography.;Antimullerian hormone. Timepoint: Two months after the PRP. Method of measurement: Blood Test.;The quality of oocyte. Timepoint: Two months after the PRP. Method of measurement: Vaginal Sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of obtained of embryo. Timepoint: Two months after the PRP. Method of measurement: Embryologist diagnosis.;The quality of resulted embryo. Timepoint: Two months after the PRP. Method of measurement: Embryologist diagnosis.;Chemical Pregnancy. Timepoint: Two weeks after the embryo transfer. Method of measurement: Blood Test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Alsadat Razavi
Tehran University of Medical Sciences
Outcome results
None listed