Non-Alcoholic Fatty Liver. Non-Alcoholic Fatty Liver (Non-Alcoholic Steato Hepatitis)
Conditions
Interventions
Intervention 1: The intervention group will take 1 gram Spirulina (platensis ) supplementation, at least one hour before the lunch meal with a glass of water, which is for 8 weeks. Supplementations c
Treatment - Drugs
The intervention group will take 1 gram Spirulina (platensis ) supplementation, at least one hour before the lunch meal with a glass of water, which is for 8 weeks. Supplementations containing Spirul
The intervention group number daily will take 1 gram Chlorella Vulgaris supplement, at least one hour before the lunch meal with a glass of water for 8 weeks. Supplements include Chlorella microalgae
Sponsors
Vice Chancellor for Research Yazd Shahid Sadoughi University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age range 20-50 years with NAFLD(Non-Alcoholic Fatty Liver) confirmed by ultrasound; have not participated in other research projects. Exclusion criteria: history of alcohol consumption; dyslipidemia who are taking medications; pregnancy and lactation; history of high blood pressure; lung disease; kidney disease; liver transplantation; complications of diabetes and chronic disorders that cause aggregation of fat in the liver such as diabetes; hepatitis use of some drugs: such as Tamoxifen; blood pressure control; statins; insulin sensitivity enhancers; hepatotoxic drugs; birth control pills and estrogen.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alanine Amino Transferase(ALT). Timepoint: Before and after 8 weeks. Method of measurement: Method :IFCC ( International Federation Clinical Chemistry) ? IU/L.;Aspartate Amin Transferase (AST). Timepoint: Before and after 8 weeks. Method of measurement: Method :IFCC ( International Federation Clinical Chemistry) ? IU/L.;Alkaline phosphatase (ALP). Timepoint: Before and after 8 weeks. Method of measurement: Method :IFCC ( International Federation Clinical Chemistry) ? IU/L.;TG (Triglyceride). Timepoint: Before and after 8 weeks. Method of measurement: Enzymatic (mg/dl).;TC (Total Cholesterol). Timepoint: Before and after 8 weeks. Method of measurement: Enzymatic (mg/dl).;LDL-C. Timepoint: Before and after 8 weeks. Method of measurement: Friedewald formula(mg/dl).;HDL-C. Timepoint: Before and after 8 weeks. Method of measurement: Deposit method(mg/dl). | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Total Antioxidant Capacity (TAC). Timepoint: Before and after 8 weeks. Method of measurement: the DPPH (Diphenyl-2-Picrylhydrazyl) percentage reduction.;Serum Malon Di Aldehyde (MDA). Timepoint: Before and after 8 weeks. Method of measurement: based on Calorimetry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactChitsazi J Maryam
School of Public Health, Yazd Shahid Sadoughi University of Medical Sciences
Outcome results
None listed