Evaluating Intra-abdominal Gas related Symptoms During Cholecystectomy

Comparison of Hemodynamic Signs and Level of Abdominal Pain in Using High and Low Pressures of Carbon Dioxide Gas in Patients Undergo Laparoscopic Cholecystectomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014121420309N1

Enrollment

Registered

2015-01-26

Start date

2014-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Cholecystectomy (Laparoscopic). Condition 2: Disorders related to gallbladder and bile ducts. Acquired absence of other parts of digestive tract Disorders of gallbladder and biliary tract in diseases classified elsewhere

Interventions

Intervention 1: First intervention group (low pressure): Usage of carbon dioxide gas with percent purity of 99% from Qazvin Oxygen Company, gas pressure: 7-10 mmhg. Intervention 2: Second intervention

Prevention

First intervention group (low pressure): Usage of carbon dioxide gas with percent purity of 99% from Qazvin Oxygen Company, gas pressure: 7-10 mmhg

Second intervention group (high pressure): Usage of carbon dioxide gas with percent purity of 99% from Qazvin Oxygen Company, gas pressure: 12-14 mmhg

Eligibility

Sex/Gender

All

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients aged 20-70 years who are candidate for laparoscopic cholecystectomy Exclusion criteria: Rupture of the gallbladder, empyema, common bile duct stones, history of major upper abdominal surgeries, pregnancy, patients with a BMI (Body Mass Index) greater than 30 or less than 19, fatty liver grade 3 or 4, abnormalities of liver enzymes before surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Mean arterial blood pressure. Timepoint: At admission, during the operation, 1, 3 and 6 hours after the surgery. Method of measurement: Monitoring.;Heart rate. Timepoint: At admission, during the operation, 1, 3 and 6 hours after the surgery. Method of measurement: Monitoring.;Body Temperature. Timepoint: At admission, during the operation, 1, 3 and 6 hours after the surgery. Method of measurement: Thermometer.	—

Measure

Time frame

Mean arterial blood pressure. Timepoint: At admission, during the operation, 1, 3 and 6 hours after the surgery. Method of measurement: Monitoring.;Heart rate. Timepoint: At admission, during the operation, 1, 3 and 6 hours after the surgery. Method of measurement: Monitoring.;Body Temperature. Timepoint: At admission, during the operation, 1, 3 and 6 hours after the surgery. Method of measurement: Thermometer.

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Secondary

Measure	Time frame
Nausea & vomiting after Laparoscopic Cholecystectomy. Timepoint: 1, 3, 6, 12 and 24 hours after the operation. Method of measurement: Verbal Rating Scale Questionnaire.;Abdominal and shoulder pain after Laparoscopic Cholecystectomy. Timepoint: 1, 3, 6, 12 and 24 hours after the operation. Method of measurement: Verbal Rating Scale Questionnaire.;Liver Tests. Timepoint: Before and after the operation. Method of measurement: Laboratory Data.	—

Measure

Time frame

Nausea & vomiting after Laparoscopic Cholecystectomy. Timepoint: 1, 3, 6, 12 and 24 hours after the operation. Method of measurement: Verbal Rating Scale Questionnaire.;Abdominal and shoulder pain after Laparoscopic Cholecystectomy. Timepoint: 1, 3, 6, 12 and 24 hours after the operation. Method of measurement: Verbal Rating Scale Questionnaire.;Liver Tests. Timepoint: Before and after the operation. Method of measurement: Laboratory Data.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDoctor Fereshteh Esmaili

Qazvin University of Medical Sciences

dr.esmaili83@gmail.com+98 28 3379 0620

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026