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Impact of fluid limitation combine with norepinephrine infusion during colorectal surgery on perioperative and post-operative complications

Hydration deferred fluid limitation combine with norepinephrine infusion on perioperative and post- operative complications during colorectal surgeries

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2014121120285N1
Enrollment
168
Registered
2015-02-22
Start date
2015-02-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Relation between fluid limitation combine with norepinephrine infusion on perioperative and post- operative complications during colorectal surgeries.

Interventions

Intervention 1: After General anesthesia in control group, routine fluid therapy was administrated. Intervention 2: After General anesthesia in intervention group , fluid limitation combine with norep
Treatment - Drugs
Early detection
After General anesthesia in control group, routine fluid therapy was administrated.
After General anesthesia in intervention group , fluid limitation combine with norepinephrine infusion (4 micro/kg/h) was administrated.

Sponsors

Tehran university of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria were: patients suffering from colorectal cancer; age group between 20 to 60 years old; nether evidence of Myocardial infarction during last 6 months nor significant cardiovascular disease; neither use of anticoagulants agent nor coagulopathy. Exclusion criteria were: severe hemodynamic instability; oliguria; anuria and significant Electrocardiographic changes during surgery.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hypotension during surgery. Timepoint: During procedure till two days after procedure. Method of measurement: Invasive Blood Pressure monitoring by Arterial Catheter.;Oliguria. Timepoint: During procedure till two days after procedure. Method of measurement: Urine Output Volume.;Duration of hospital admission after surgery. Timepoint: Time of discharging from hospital. Method of measurement: According to clinical file.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShervin Malekzadeh

Tehran University of Medical Sciences

shervinmalekzadeh@irimc.org+98 21 6119 2828

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026