Comparing the effect of Therapeutic Doses of 200 and 50000 Units of Vitamin D on Serum 25(OH)D Levels in Pregnant Women Referred to Shahid Sayyad Shirazi Hospital of Gorgan between 2013-14

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2014121120276N1

Enrollment

Registered

2016-09-24

Start date

2014-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamon D Deficiency. Vitamin D Dificiency

Interventions

Intervention 1: Group A will be treated with 200 IU of vitamin D supplements orally for 8 weeks. Intervention 2: The women in group B will be treated with 50,000 IU of vitamin D supplements orally wee

Treatment - Drugs

Group A will be treated with 200 IU of vitamin D supplements orally for 8 weeks.

The women in group B will be treated with 50,000 IU of vitamin D supplements orally weekly for 8 weeks

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria included gestational age 12-16 weeks based on first trimester ultrasound or accurate LMP; nulliparity; singleton pregnancy; vitamin D deficiency. Exclusion criteria included incomplete treatment of supplements or impossible follow-up; a history of high-risk pregnancy; a history of parathyroid disease; hypocalecemia or hypercalcemia; underlying disease such as liver disease, renal disease; hypertension and malabsorption disorders (based on medical history or personal statements); diabetes (based on routine tests done during pregnancy).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Efficacy of different doses of vitamin D supplements and treatment of vitamin D deficiency in pregnant women. Timepoint: 20 weeks after intervention. Method of measurement: Measurement of serum levels of 25 (OH) D in ng/dl.	—

Secondary

Measure	Time frame
Prevention of maternal and neonatal complications of pregnancy. Timepoint: 20 weeks after intervention. Method of measurement: Evaluation on term delivery in terms of complications.;Safety of treatment with vitamin D supplement. Timepoint: 20 weeks after intervention. Method of measurement: Evaluation on term delivery in terms of hypervitaminosis and drug side effects.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Malihe Azadehrah

Golestan University of Medical Sciences

m.azadehrah@gmail.com+98 17 3226 1150

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026