Spinal anesthesia. Unspecified adverse effect of drug or medicament
Conditions
Interventions
Intervention 1: pregabalin group (150 mg capsule): because of 150 mg capsules it's not available on the market of Iran that is given two 75 mg capsules instead. A hour before spinal anesthesia is use
Treatment - Drugs
pregabalin group (150 mg capsule): because of 150 mg capsules it's not available on the market of Iran that is given two 75 mg capsules instead. A hour before spinal anesthesia is used by nurses in t
placebo group (Appearance, but no active ingredient drug capsules ). A hour before spinal anesthesia is used by nurses in the orthopedic unite, who was not aware of drugs the patient is given effect
Sponsors
Deputy for research Zahedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: The non-emergency patients ASA class 1; Age 20 to 70 years; candidates for orthopedic surgery tibia fracture; the prior written consent from patient; social class and level of consciousness that patient is able to cooperate ; Exclusion criteria were the beginning of the study: hemodynamic status is affected with diseases or conditions such as heart disease, diabetes, renal ;The history of allergy to gabapentin or Pregabalin, drug use, regular use of alcohol or smoking more than 5 years, the diseases of the brain and nerves ; spinal anesthesia during surgery after more than ninety minutes ; patients who require drugs that affect hemodynamic ; pregnancy ; refusal of doing research and refusal of spinal anesthesia patients ; patients with coagulopathy ; infection in site of the spinal anesthesia ; any interference with the absorption of oral drugs that can cause digestive disorders ; The disease affects the feeling of pain, such as diabetes, drug addiction ; Monitor the patient is indicative of Abnormal pulse , mean arteria presure ; The need for analgesics for pain relief Exclusion criteria during the study: Abnormal bleeding during surgery ; Intraoperative cardiovascular and brain complications ; Monitor the patient is indicative of abnormal pulse, mean arterial pressure.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure? pulse. Timepoint: Thirty minutes before feeding capsules every ten minutes. Every ten minutes after spinal anesthesia to complete the surgery. Method of measurement: Monitoring of vital signs.;Duration of analgesia in spinal anesthesia. Timepoint: After the onset of anelgesia by spinal anesthesia Until the onset of pain. Method of measurement: Timer(minute). | — |
Secondary
| Measure | Time frame |
|---|---|
| No exist. Timepoint: No exist. Method of measurement: No exist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Moosavi
Zahedan University of Medical Sciences
Outcome results
None listed