Investigation of the effects of vaginal probiotic capsules on prolonging the time of membrane rupture up to delivery and on maternal and fetal complications.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141209020264N3

Enrollment

Registered

2018-03-19

Start date

2017-10-23

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prevention of Preterm delivery and maternal and fetal complications. Preterm labour without delivery

Interventions

Intervention 1: Intervention group: for pregnant women with premature membrane rupture, in the first 48 hours of hospitalization, 2 grams of intravenous Ampicillin injection per 6 hours and then for a

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: live singleton pregnancy being pregnant for 24 to 32 weeks no symptoms of chorioamniotic no sign of fetal distress no vaginal bleeding consent of mothers to participate in the study

Exclusion criteria

Exclusion criteria: sings of chorioamniotic disturbed fetal health assessment test vaginal bleeding unwillingness of patients to continue participating in the study

Design outcomes

Primary

Measure	Time frame
Prolonging the time of membrane rupture up to 34 weeks. Timepoint: Precise control of mother's vital signs and fetus health, two times of sonography during a week and CBC every other day. Method of measurement: Fetus health is evaluated through NST.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Azam Pourhoseini

Mashhad University of Medical Sciences

pourhoseinia@mums.ac.ir+98 51 3801

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026