Role of phyto-oestrogens (Cimicifuga racimosa) in combination with clomiphene citrate on ovulation induction in women with polycystic ovarian syndrome

Role of phyto-oestrogens (Cimicifuga racimosa) in combination with clomiphene citrate on ovulation induction in women with poly-cystic ovarian syndrome, A clinical Trial study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141209020264N2

Enrollment

100

Registered

2018-01-04

Start date

2016-12-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

polycystic ovarian syndrom. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: 20 mg Cimicifuga racimosa twice a day for 10 days with clomiphene citrate 50 mg twice a day for 5 days. The regimen will be started from the second day of the menst

Treatment - Drugs

Intervention group: 20 mg Cimicifuga racimosa twice a day for 10 days with clomiphene citrate 50 mg twice a day for 5 days. The regimen will be started from the second day of the menstrual cycle and w

Control group: clomiphene citrate 50 mg twice a day for 5 days. The regimen will be started from the second day of the menstrual cycle and will be prescribed for three consecutive cycles.

Eligibility

Sex/Gender

Female

Age

20 Years to 38 Years

Inclusion criteria

Inclusion criteria: Women with polycystic ovarian syndrome Primary and secondary infertility Normal hysterosalpingography Normal Spermogram in patients' spouses Age below 38 years

Exclusion criteria

Exclusion criteria: History of cardiovascular disease History of liver disease History Ovarian masses

Design outcomes

Primary

Measure	Time frame
Plasma estradiol. Timepoint: 12 days after intervention. Method of measurement: sonography.	—

Secondary

Measure	Time frame
Endometrial thickness. Timepoint: 12 days after intervention. Method of measurement: sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMalihe Mahmoodo Nia

Mashhad University of Medical Sciences

mahmodynia@gmail.com+98 51 3802 2608

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026