Comparison effect of subcutaneous Dexmedetomidine and subcutaneous Marcaine 0.5 % in hemodynamic changes and sedation during hernia surgery

Comparison effect of subcutaneous Dexmedetomidine and subcutaneous Marcaine 0.5 % in hemodynamic changes and sedation during hernia surgery and management of pain after surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141209020258N99

Enrollment

120

Registered

2019-03-20

Start date

2018-08-23

Completion date

Unknown

Last updated

2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hernia surgery. Inguinal hernia

Interventions

Intervention 1: Intervention group 1: We inject 5 milligram Marcaine 0.5% (Aboreihan Co) and 1 micro gram in kilogram Dexmedetomidin(PFIZER [America]) and distilled water.Final volume is 10 millilit

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 18 years old to 65 years old ASA Class I and II Candidates for hernia surgery Body mass index less than 30 No allergy to used drugs Lack of underlying illness No smoking and addiction

Exclusion criteria

Exclusion criteria: Dissatisfaction with participating in the study Refusal to undergo intra cutaneous injection

Design outcomes

Primary

Measure	Time frame
Mean arterial blood pressure. Timepoint: Every 5 minutes to the end of surgery and recovery. Method of measurement: Barometer.;Heart rate. Timepoint: Every 5 minutes to the end of surgery and recovery. Method of measurement: Beat in minute.;Oxygen saturation. Timepoint: Every 5 minutes to the end of surgery and recovery. Method of measurement: Oximeter.;Pain. Timepoint: At recovery and at 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Questionnaire visual analogue scale.	—

Measure

Time frame

Mean arterial blood pressure. Timepoint: Every 5 minutes to the end of surgery and recovery. Method of measurement: Barometer.;Heart rate. Timepoint: Every 5 minutes to the end of surgery and recovery. Method of measurement: Beat in minute.;Oxygen saturation. Timepoint: Every 5 minutes to the end of surgery and recovery. Method of measurement: Oximeter.;Pain. Timepoint: At recovery and at 2, 4, 6, 12, and 24 hours after surgery. Method of measurement: Questionnaire visual analogue scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hesamedin Modir

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026