Comparison effects of Melatonin premedication on Propofol and induction ?dose in abdominal surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141209020258N98

Enrollment

Registered

2019-02-22

Start date

2017-04-04

Completion date

Unknown

Last updated

2019-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

abdominal surgery. Transient alteration of awareness

Interventions

Intervention 1: Intervention group: We inject 3 milligram Melatonin sublingual (Canadian manufacturer Inter natural - 3 milligrams) 50 minute before surgery (volume is brought to 3 milliliter). Interv

Eligibility

Sex/Gender

All

Age

15 Years to 55 Years

Inclusion criteria

Inclusion criteria: 15-55 years Non-emergency abdominal surgery Surgery time 30 minutes to 1 hour and a half body mass index 19 to 25 No drug use during the past week No use of benzodiazepine-derived drugs over the past 72 hours

Exclusion criteria

Exclusion criteria: Dissatisfaction

Design outcomes

Primary

Measure	Time frame
Anxiety. Timepoint: before and after intervention. Method of measurement: Visual analog scale.;Awareness. Timepoint: before and after intervention. Method of measurement: Visual analog scale.;Sedation. Timepoint: before and after intervention. Method of measurement: Visual analog scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Shahin Fateh

Arak University of Medical Sciences

sh.fateh@arakkmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 22, 2026