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Comparison of therapeutic effects and its outcomes with morphine against methadone in combination with diazepam and haloperidol in cancer patients with severe and chronic pain referred to emergency ward.

Comparison of therapeutic effects and its outcomes with morphine against methadone in combination with diazepam and haloperidol in cancer patients with severe and chronic pain referred to emergency ward.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N93
Enrollment
92
Registered
2019-01-09
Start date
2018-06-22
Completion date
Unknown
Last updated
2019-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer. Malignant neoplasm, primary site unspecified

Interventions

Intervention 1: Intervention group: We inject 5 milligram Metadon and 5 milligram Haloperidol in muscular and 10 milligram Diazpam intravenous slowly for 5 minute in first group. Intervention 2: Inter

Sponsors

Vice Chancellor For Research, Arak University Of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All patients with metastatic disease of spine with pain complaints and scurvy of pain 7 and above referring to Emergency hospital of Amiralmomenin and Vali Asr arak Hospital Non-allergic to benzodiazepine and haloperidol

Exclusion criteria

Exclusion criteria: Unsatisfied patients Decreased consciousness at the time of referral or during the study Blood pressure drop of SBP <90 at the time of referral or during the study There is any contraindication in the administration of opioid or Benzodiazepine or Haloperidol Patients with scores of pain less than 7 Oxygen saturation below 92% Heart rate above 90 or under 60

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: 1 and 24 hours after intervention. Method of measurement: Visual analog scale.;Patient satisfaction. Timepoint: 24 hours after intervention. Method of measurement: observation.;Side effect of drugs. Timepoint: After intervention. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Ramin Parvizrad

Arak University of Medical Sciences

parvizrad@arakmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026