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Comparison of premedication Dexmedetomidine and remifentanil and Labetalol before ECT on hemodynamic responses and seizure time in patients

Comparison of premedication Dexmedetomidine and remifentanil and Labetalol before ECT on hemodynamic responses and seizure time in patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N89
Enrollment
144
Registered
2018-12-16
Start date
2018-08-23
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychotic patients. Psychotic disorder with hallucinations due to known physiological condition

Interventions

Intervention 1: Intervention group: We inject 0/5 micro gram in kilogram Dexmedetomidin. Intervention 2: Intervention group: We inject 0/2 milliliter in kilogram Labtalol. Intervention 3: Control grou

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 60 Years

Inclusion criteria

Inclusion criteria: 16-60 years both of gender No history of drug use Not pregnancy No history of cardiovascular disease (arrhythmia, ischemia, heart block) No taking beta-blocker medication Insensitivity to the drugs used in this study Patients with schizophrenia diagnosis

Exclusion criteria

Exclusion criteria: Lack of consent to cooperate Patients who require more than 60% energy for tonic clonic seizures. Patients whose clonic tonic seizures are less than 25 seconds. All patients with ECT undergoing arrhythmia or hemodynamic threatening changes requiring intervention therapies.

Design outcomes

Primary

MeasureTime frame
Blood pressure. Timepoint: Start, 1 and 5 and 10 minute before ECT and every 5 minute after ECT to transfer to hospital section. Method of measurement: Barometer.;Heart rate. Timepoint: Start, 1 and 5 and 10 minute before ECT and every 5 minute after ECT to transfer to hospital section. Method of measurement: Count.;Seizure duration. Timepoint: Duration ECT. Method of measurement: Minute.;Recovery duration. Timepoint: After ECT. Method of measurement: Minute.;Satisfaction. Timepoint: After ECT. Method of measurement: Check list.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hesamedin Modir

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026