Acute sepsis. Streptococcal sepsis, unspecified
Conditions
Interventions
Intervention 1: Intervention group: En Immediately after the initial diagnosis patients in the intervention group (30), one gram of ?morophenem in one bolus and 100 milligram in hours of antibiotic ma
Treatment - Drugs
Intervention group: En Immediately after the initial diagnosis patients in the intervention group (30), one gram of ?morophenem in one bolus and 100 milligram in hours of antibiotic maroponum, receive
Control group: Patients in the control group (n = 30) received one gram of moropenum as bolus dosing ?every 12 hours and 10 cc per hour of normal saline for continuous infusion over a period ?of 72 .
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 18-75 years Patients admitted to ICU with the diagnosis of evidence of infection and at least two of the symptoms of SIRS (sepsis)
Exclusion criteria
Exclusion criteria: Incidence of drug-related complications No response to treatment within 72 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Procalcitonin. Timepoint: Before and 2 weeks after treatment. Method of measurement: milligram.;GFR. Timepoint: Before and 2 weeks after treatment. Method of measurement: count.;Level of consciousness. Timepoint: At the time of arrival, 24, 48 and 72 hours after receiving the drug. Method of measurement: Glasgow scale.;Incidence of mortality. Timepoint: Before and 2 weeks after treatment. Method of measurement: Number. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Alireza Kamali
Arak University of Medical Sciences
Outcome results
None listed