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Comparison effect of Apotel and Pergabalin in reduce pain after ?in orthopedic surgery ?

Comparison effect of Apotel and Pergabalin in reduce pain after ?in orthopedic surgery ?

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N61
Enrollment
75
Registered
2018-01-09
Start date
2017-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain after surgery. Pain, not elsewhere classified

Interventions

Intervention 1: Intervention group: We treat patients 150 miligeram pregabalin 2 hours before surgery in intervention group.?. Intervention 2: Intervention group: We treat patients 1 gram Apotel in 2
Treatment - Drugs
Intervention group: We treat patients 150 miligeram pregabalin 2 hours before surgery in intervention group.?
Intervention group: We treat patients 1 gram Apotel in 200 milliliter 20 minute before surgery in intervention group.?
Control group: We treat patients one capsule placebo before surgery in intervention group.?

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to 65 Years

Inclusion criteria

Inclusion criteria: candidate orthopedic surgery ?lower limb 17 to 65 years both of two gender

Exclusion criteria

Exclusion criteria: Coagulation disorders Unwillingness to participate in the study Severe hemodynamic instability Hepatic, renal and cardiac disease Sensitivity to Pregabalin and Apotel

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: We record pain in recovery, 2 and 12 and 24 hours after surgery. Method of measurement: Visual Analog Sacle.;Consumption of opioids. Timepoint: We record consumption of opioids in 24 hours in milligram. Method of measurement: milligram.;Sedation. Timepoint: We record ramsy sedation score in 24 hours after surgery.?. Method of measurement: ramsy sedation score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Alireza Kamali

Arak University of Medical Sciences

alikamaliir@yahoo.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026