Craniotomy surgery. Craniorachischisis
Conditions
Interventions
Intervention 1: Intervention group 1: 1 µg/kg of dexmedetomidine for 10 minutes as an initial dose, followed by 0.4 to 0.8 µg/kg per hour for maintenance dose. (Consumable dexmedetomidine is made by E
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Age 18 to 75 years ASA class Iand II Absence of coagulation disorders No history of cardiovascular diseases Proper control of blood pressure Absence of pregnancy No addiction to opioids Body mass index less than 35 Craniotomy candidate patients Having consent to enter the study Absence of sensitivity to the study drugs The presence of creatinine less than 1/5 Absence of platelet count less than 150 thousand Serum magnesium is less than or equal to 2.5
Exclusion criteria
Exclusion criteria: Dissatisfaction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average hemoglobin. Timepoint: Before and 12 hours after surgery. Method of measurement: Blood test.;Bleeding. Timepoint: during surgery. Method of measurement: Based on scoring 1 to 4 bleeding volume.;Consent of the surgeon. Timepoint: After surgery. Method of measurement: Score 3 points(zero means bad, one means average and two means good).;Recovery time. Timepoint: End of study. Method of measurement: chronometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Hesamedin Modir
Arak University of Medical Sciences
Outcome results
None listed