Skip to content

Comparison of the effect of adding midazolam, paracetamol, tramadol and magnesium sulphate to ?ropivacaine in reducing pain

Comparison of the effect of adding midazolam, paracetamol, tramadol and magnesium sulphate to ?ropivacaine in reducing pain and hemodynamic changes in intravenous local anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N168
Enrollment
160
Registered
2021-11-05
Start date
2021-11-22
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Forarm surgery. Unspecified injury of ulnar artery at forearm level, right arm, sequela

Interventions

Intervention 1: Intervention group 1: 50 milligram in kilogram of magnesium sulfate 50% made by Shahid Ghazi Pharmaceutical Company of Tabriz with rupivacaine two tenths of a percent will inject. Inte

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate of forearm surgery ASA class 1 and 2 No Raynaud's disease Absence of any vascular disease No sickle cell anemia No history of allergy to the drugs used in the study Lack of cyanosis of the affected limb Do not use drugs and psychotropic substances No contraindication to intravenous anesthesia No more than one fracture in the body or surgery Absence of chronic pain syndrome Absence of neurological disorders in the hand

Exclusion criteria

Exclusion criteria: For any reason, local intravenous anesthesia may be terminated during surgery Not consent to participate in study Duration of operation less than 30 minutes or more than 90 minutes

Design outcomes

Primary

MeasureTime frame
Sensory block. Timepoint: From the beginning study to 24 hours. Method of measurement: Physical examination.;Motor block. Timepoint: From the beginning study to 24 hours. Method of measurement: Physical examination.;Pain. Timepoint: After filling the tourniquet, 15, 30 and 45 minutes after the start of surgery and 30, 60, 90 and 120 minutes after the end of surgery. Method of measurement: Visual analogue pain questionnaire.;Average use opioids. Timepoint: Within 24 hours after surgery. Method of measurement: View file.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Esmaeel Moshiri

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026