Skip to content

Comparison of Zolpidem and melatonin in postoperative pain control in intervertebral disc herniation surgery under general anesthesia

Comparison of Zolpidem and melatonin in postoperative pain control in intervertebral disc herniation surgery under general anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N161
Enrollment
60
Registered
2021-06-22
Start date
2021-06-15
Completion date
Unknown
Last updated
2021-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herniated lumbar intervertebral disc. Other intervertebral disc displacement, lumbar region

Interventions

Intervention 1: Intervention group 1: We will prescribe 6 milligram of sublingual melatonin (Webber Natural Co) dissolved in water (final volume 5 ml) 90 minutes before surgery. Intervention 2: Interv

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate for intervertebral disc herniation surgery 17 to 65 years Both gender Absence of coagulation disorders Absence of liver disease and renal disease and heart disease No history of drug use in the last 48 hours No addiction to drugs, psychedelics and alcohol Lack of sensitivity to the studied drugs Lack of platelet count less than 150 thousand No family history of thromboembolism Absence of severe hemodynamic instability L2 - L5 surgery and laminectomy

Exclusion criteria

Exclusion criteria: Reluctance to participate in the study

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: During recovery and at 2, 4, 6, 12 and 24 hours after surgery. Method of measurement: Visual analog scale of pain.;Mean of narcotics consumption. Timepoint: 24 hours after surgery. Method of measurement: Patient file.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Esmaeel Moshiri

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026