Comparison of the effect of vitamin C and N-acetyl cysteine (NAC) on improving clinical symptoms and reducing the duration of hospitalization in patients with covid-19

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141209020258N160

Enrollment

232

Registered

2021-06-06

Start date

2021-06-15

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Covid-19. COVID-19, virus identified

Interventions

Intervention 1: Intervention group 1: Vitamin C tablets with a dose of 1 gram are given every 8 hours for 5 days. Intervention 2: Intervention group 2: N-acetylcysteine tablets at a dose of 600 mg eve

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years No pregnancy or breastfeeding Absence of G6PD deficiency No history of calcium oxalate kidney stones Lack of sensitivity to drugs

Exclusion criteria

Exclusion criteria: Dissatisfaction

Design outcomes

Primary

Measure	Time frame
Duration of hospitalization in the intensive care unit. Timepoint: During the intervention. Method of measurement: Observation.;Percentage of oxygen saturation. Timepoint: During the intervention. Method of measurement: Pulse oximetry.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Behnam Mahmodie

Arak University of Medical Sciences

mahmodie@arakmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026