Comparison of sedation and hemodynamic changes resulting from administration of ?dexmedetomidine, ketamine and Etomidate with propofol during cataract surgery by ?Phacoemulsification method

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20141209020258N156

Enrollment

128

Registered

2021-04-25

Start date

2021-05-05

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract surgery. Age-related cataract

Interventions

Intervention 1: Intervention group: Dexmedetomidine is administered intravenously at a dose of 0.5 µg / kg. (Madonex ampoule 100 micro grams per millilitre made by Exir Pharmaceutical Company - Iran).

Eligibility

Sex/Gender

All

Age

35 Years to 85 Years

Inclusion criteria

Inclusion criteria: Candidate for cataract surgery by Fico method Age 35 to 85 years Absence of mental disorders Lack of history of chronic use of sedatives No alcohol and drugs Absence of severe obstructive pulmonary disease and asthma No history of heart disease, heart block and bradycardia Absence of systolic blood pressure less than 90 mm Hg Absence of severe liver and renal failure Absence of uncontrolled diabetes Absence of cerebrovascular diseases

Exclusion criteria

Exclusion criteria: Patient dissatisfaction

Design outcomes

Primary

Measure	Time frame
Sedation. Timepoint: Every 5 minutes during surgery and in recovery and 1, 2 and 4 hours after surgery. Method of measurement: Ramsay score.;Pain. Timepoint: During surgery every 5 minutes and during recovery and 1, 2 and 4 hours after surgery. Method of measurement: Visual analog pain score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Esmaeel Moshiri

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026