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Comparison of intrathecal injections of Meperidine, Teramadol, Magnesium sulfate and Dexmedetomidine in prevention of shivering and postoperative complications of femoral fracture repair under spinal anesthesia

Comparison of intrathecal injections of Meperidine, Teramadol, Magnesium sulfate and Dexmedetomidine in prevention of shivering and postoperative complications of femoral fracture repair under spinal anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20141209020258N153
Enrollment
132
Registered
2021-03-09
Start date
2021-03-15
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femoral fracture repair under spinal anesthesia. Other complications of anaesthesia

Interventions

Intervention 1: Intervention group: They receive 5 micrograms of dexmedetomidine along with 12.5 mg of hyperbaric bupivacaine 0.5% (2.5 ml). (Dexmedetomidine Elixir Pharmaceutical Company - Iran). Int

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age: 18 to 75 years old Both sexes ASA Class 1 and 2 Femoral fracture repair under spinal anesthesia No history of drug addiction No history of seasonal allergies as well as allergies to any of the drugs used in this study Absence of neuromuscular diseases Absence of Raynaud's disease Absence of cardiomyopathy Absence of coagulation disease

Exclusion criteria

Exclusion criteria: Failure in anesthesia and other methods Dissatisfaction with continuing to participate in the project

Design outcomes

Primary

MeasureTime frame
Shivering intensity. Timepoint: In recovery and every 15 minutes to 2 hours and then every 2 hours to 12 hours. Method of measurement: Fourth criterion (0-3): 0 means no shivering, 1 means mild fasciculation of the face and neck, 2 means visible tremor in more than one muscle, and 3 means intense muscle activity throughout the body.;Sedation. Timepoint: During the operation and up to 12 hours after the operation. Method of measurement: Ramsay Sedation Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Esmaeel Moshiri

Arak University of Medical Sciences

modir.he@gmail.com+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 10, 2026